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Ada Wong is the mysterious long-legged femme-fatale of the Resident Evil franchise. She is generally portrayed as cold and calculating but tends to soften when her mission comes into conflict with Leon S. Kennedy.
Agent 47 is the main protagonist of the Hitman franchise; including games, films and novels. His name is derived from the last two digits off the barcode tattooed on the back of his head (640509-040147) as well as the fact he has 47 chromosomes.
Ajunta Pall was the first Dark Lord of the Sith, a title he took after having been exiled from the Jedi Order. In Star Wars: Knights of the Old Republic, the player can meet Ajunta's spirit while exploring his tomb.
Airyglyph's general of the Black Brigade. He's a very skilled swordsman from Star Ocean: Till the End of time.
The protagonist of Prototype, Alex Mercer has been transformed by a virus into a shapeshifting weapon. He seeks to uncover the mysterious source of his abilities as well as fight the same virus as it consumes Manhattan.
Dracula's not-quite-so-loving son from the Castlevania franchise. He is a vampire who fights against his father on the side of good.
Famous for his enormous size and strength, the late André "the Giant" Roussimoff was a particularly beloved WWF wrestler who also appeared in many video games, continuing to be included in game rosters for years after his death. These include WWF Superstars and Wrestlemania on the NES.
Android 16 is an android created by Dr. Gero to kill Goku. He was considered a failure and remained deactivated until Android 17 killed Gero and activated him.
Twin brother of Android 18 (technically Cyborgs in this case) Android 17 was created by Dr. Gero, but rebelled and killed him. 17 is absorbed by Cell and dies with him, but is later wished back to life with Cell's victims. He becomes a Park Ranger and starts a family.
Twin sister of Android 17, the only female "Android" (actually a Cyborg in this case) created by Dr. Gero. 18 is absorbed by Cell to transform into his Perfect Form, but is later spat back out. She marries Krillin and they have a daughter, Marron.
Angel (Experiment 624) is Stitch's pink girlfriend who looks a lot like him and has a beautiful singing voice, with a siren song that converts reformed experiments made before her back to evil (or back to good if she sings backwards). Stitch's love and kindness towards her (and his immunity to her siren song) caused her to reform herself and fall in love with him. She later became a pop singer in the anime "Stitch!".
Initially known as The Thief, Angela worked for MegaCorp before quitting to help Ratchet destroy the Protopet
The Marvel Cinematic Universe's Taskmaster, brainwashed by her father into acting as his top agent and enforcer.
The man who reluctantly ordered Andraste's execution but then granted her a mercy-kill, making him a legendary figure in the Chantry faith
The Greek god of war Ares in the Marvel Universe is often a villain, and was part of Norman Osborn's Dark Avengers.
Asajj Ventress is a Sith assassin appearing in the Star Wars: Clone Wars TV show, movie, and comics. She tries on multiple accounts to kill both Anakin Skywalker and Obi-Wan Kenobi.
Ashi is a daughter of Aku and Samurai Jack's love interest.
Despite being a demon in origin, Ashrah is a demon hunter in the Mortal Kombat series who seeks to purify herself with her enchanted kriss.
A decadent Elven Vampire-Spawn who has long looked for a way to escape his master's influence. One of the companions in Baldur's Gate 3.
Antagonist character from the RPG "Nostalgia." She has the power to change her appearance.
Atton Rand is the second character to join your party in Knights of the Old Republic II. He is a gambling, untrusting, smuggler.
A character in the Kingdom Hearts franchise. Organization member VIII and was good friends wtih Roxas before he merged with Sora.
"HUZZAH!"
Playable Support Hero in Overwatch. A Haitian special operations combat medic who joined the Talon mercenary group, becoming hunted by them once he abandoned the group.
One of the fiercest Tarkatans, a group of nomadic mutants from the Outworld realm. He became one of Shao Kahn’s most favored enforcers for his ferocious strength and his retractable arm blades. Many of Shao Kahn’s enemies have fallen to Baraka’s might.
A sardonic, laid-back talking bat who works for Rasputin in Don Bluth's Anastasia movie.
An adversary turned ally in Lost Planet.
Bastila Shan is a Jedi Sentinel of considerable talent and ability, although she is headstrong and a little impulsive. She is a primary character in BioWare's seminal entry into the Star Wars universe, Star Wars: Knights of the Old Republic.
One of the main characters of "The World Ends With You".
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