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While they spent much of their lives at odds with one another, Solid Snake and Big Boss made amends right before Big Boss' passing.
Chris Jenner is an ally to Solid Snake and the last surviving member of Delta Force. She and Delta Squad were sent into Galuade preemptively to gather intel for Snake.
Solid Snake told Naomi that he only had two friends, one of which being Roy Campbell.
A member of Snake's support staff in the first Metal Gear game.
The male scientist that developed the original TX-55 Metal Gear unit. Held hostage by Big Boss in the original Metal Gear, he became Big Boss's ally in Metal Gear 2.
Despite Drebin claiming that he was neither enemy nor friend, Old Snake's mission probably would not have had the success it did if were not for Drebin.
Old Snake accompanied the Rat Patrol in their successful missions, which earned Ed's respect.
The daughter of the scientist Drago Pettrovich Madnar. In the original Metal Gear, she was held hostage in Outer Heaven to secure Dr. Madnar's cooperation.
Solid Snake, under the guise of Iroquois Pliskin, covered Emma while she was moving across the struts at the Big Shell.
Eva is Solid Snake's birth mother, and he held her in his arms as she died.
Solid Snake mentioned that Frank Jaeger was his friend during a conversation with Naomi in spite of them being at odds on the battlefield.
A former lover of Gray Fox, she appears in Metal Gear 2: Solid Snake where she helps Snake communicate with Dr. Marv.
A CIA operative who posed as a journalist to infiltrate Zanzibar Land, where she provided support to Solid Snake.
A member of Snake's support staff in the first Metal Gear.
Jimmy Harks is a boy genius and the scientist in charge of Project Babel for The General in Galuade. After the completion of Metal Gear he is held captive, but is eventually found and freed by Solid Snake and Chris Jenner.
Snake supported the Rat Patrol and covered Johnny Sasaki during the battles. Snake was even invited to Johnny and Meryl's wedding.
Old Snake accompanied the Rat Patrol during Liquid's insurrection and covered Jonathan.
A Czech biologist who appears in Metal Gear 2: Solid Snake. The rescue of him and his OILIX formula is the mission in the game.
In the Metal Gear Acid timeline, Solid Snake accompanied Leone during his death and there was a mutual respect.
Old Snake gave Little Gray a few of his cigarettes during Liquid's Insurrection.
Master Miller helped train Solid Snake in his younger career, and Snake even admitted that there was nobody he trusted more.
Mei Ling was on the support team during the Shadow Moses incident, and Solid Snake kept in touch with her afterwards.
Solid Snake rescued Meryl during the Shadow Moses Incident. Meryl was in the cell next to the DARPA Chief and heard the entire conversation between Snake and the DARPA Chief, she also heard when the DARPA Chief succumbed to FOXDIE. Meryl then knocked out the guard near her cell and took his clothing, then she let Snake out, where they met for the first time pointing a gun at each other. After the Shadow Moses Incident, the two rode off into the sunset in what was a "happy ending." However, the they would eventually split up for unknown reasons. Meryl would finally meet up with Snake again 9 years after the Shadow Moses Incident in the Middle East during Guns of the Patriots. She was Snake's informant and revealed the location of Liquid Ocelot for him. Meryl would aid Snake again in Europe, and on Outer Haven where she finally got the chance to protect Snake this time.
Solid Snake, who is not one for grudges, did not seem to hold any animosity for Naomi for infecting him with FoxDie.
Solid Snake leaked the truth regarding the Shadow Moses incident to Nastasha who wrote a book regarding it.
Otacon and Solid Snake were truly friends from the time they met to to the end of Metal Gear Solid 4: Guns of the Patriots.
Peter Stillman gave Snake the coolant spray that disarmed the C4 on the Big Shell.
A Pipo-Monkey based off of Solid Snake's DNA.
Raiden is one of the main characters in the Metal Gear series. He has gone from an Army XXI grunt, to a soldier whose abilities rival the legendary Solid Snake, to a cyborg ninja with superhuman capabilities.
A member of the CIA, Roger McCoy acts as the leader in Metal Gear Acid.
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