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The title character of the XBLA game 'Splosion Man. A dangerous folly of man (and science!), originally designed as a weapon, this 'Splosion without a cause fights his way through the ranks of Big Science Labs in a last ditch bid for freedom the only way he knows how, 'Splodin'.
A traitor and enemy to the vast majority of Resident Evil's protagonists, Albert Wesker has rapidly achieved super-villain status within the series canon.
An Umbrella researcher, Annette is the wife of fellow researcher William Birkin to which they have a single child, Sherry Birkin.
Ben is the supposed leader of the Others on the Island.
Personal assistant of Aperture Science CEO Cave Johnson in Portal 2. Her digitised conciousness was the basis for GLaDOS.
Founder and CEO of Aperture Science, Johnson is a constant overseer of Aperture tests by way of prerecorded voice messages.
Chell is the silent protagonist of Portal who is set with the task of breaking several laws of physics in order to make her way through the Aperture Science Enrichment Center.
The man who created Crackdown's Super-Human Agents and The Agency's Cloning Program. He is responsible for Crackdown's Freaks
Excella Gionne is the head of the African branch of the TriCell Pharmaceutical Company. She has allied herself with Albert Wesker in Resident Evil 5.
The Genetic Lifeform and Disk Operating System of the Aperture Science Enrichment Center in Portal. GLaDOS is a maniacal, rogue AI known for her disdain for humans and unintentionally humorous nature.
The star of the Tomb Raider series and one of the earliest female video game protagonists. British treasure hunter Lara Croft has become one of the most widely recognized game characters in history.
A top Lieutenant in Cerberus, Miranda oversaw the Lazarus Project, a project dedicated to bringing Commander Shepard back from the dead. She eventually joins Commander Shepard aboard the Normandy.
Professor Hojo is a villain in Final Fantasy Vll. He is responsible for experiments conducted on some of the games most prominent characters.
Wheatley is a personality sphere in charge of all human test subjects in the Aperture Science Computer-Aided Enrichment Center. In Portal 2, he serves as the player's companion and guide. He is voiced by Stephen Merchant.
William Birkin is a former co-worker of Albert Wesker. He created the G-Virus and is partially responsible for the outbreak that destroyed Raccoon City.
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