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The title character of the XBLA game 'Splosion Man. A dangerous folly of man (and science!), originally designed as a weapon, this 'Splosion without a cause fights his way through the ranks of Big Science Labs in a last ditch bid for freedom the only way he knows how, 'Splodin'.
A traitor and enemy to the vast majority of Resident Evil's protagonists, Albert Wesker has rapidly achieved super-villain status within the series canon.
Alfred Ashford's sister, presumed dead.
One of the main male characters in Resident Evil Code: Veronica. He is a descendant of one of the founders of Umbrella.
The last mission is in a laboratory.
A socially-inept inventor who became Asgore's royal scientist.
Dr. Amanda Kenson is a human scientist most famous for her discoveries around the origin of the Mass Relays.
Android 16 is an android created by Dr. Gero to kill Goku. He was considered a failure and remained deactivated until Android 17 killed Gero and activated him.
Twin brother of Android 18 (technically Cyborgs in this case) Android 17 was created by Dr. Gero, but rebelled and killed him. 17 is absorbed by Cell and dies with him, but is later wished back to life with Cell's victims. He becomes a Park Ranger and starts a family.
Twin sister of Android 17, the only female "Android" (actually a Cyborg in this case) created by Dr. Gero. 18 is absorbed by Cell to transform into his Perfect Form, but is later spat back out. She marries Krillin and they have a daughter, Marron.
Android 19 was created by Dr. Gero to kill Goku. Unlike his previous creations, Android 19 is completely mechanical, and designed to absorb his opponent's life energy.
A research scientist.
Arachnus is a creature who is fought in both Metroid II and Metroid Fusion.
the Female Protagonist of Mega Man ZX Advent. She is a Treasure hunter that gets involved in deeper issues when she meets Model A.
This is the Security robot encountered by Samus on board the BSL research station.
Baby Head is one of four playable characters in Capcom's 2D bat 'em up: Captain Commando.
Boxer in the Street Fighter universe. His character was based on the real life boxer Mike Tyson.
The inventor of the Mouser, Baxter Stockman is a scientist who is often in the employ of The Shredder. He ends up either a cyborg or a mutant fly depending on the incarnation.
Bryan Fury is a character in the popular Tekken fighting game series. He was killed in a Hong Kong shootout, only to be revived by Dr. Abel with the use of cybernetic equipment, effectively making him a zombie cyborg.
Bubbles was Michael Jackson's pet chimpanzee. In Michael Jackson's Moonwalker, Bubbles aids Michael by hopping on his shoulders and pointing him towards the end of the level.
Experiment 621, also known as Chopsuey according to the film "Leroy & Stitch", is one of Dr. Jumba Jookiba's genetic experiments. He is the secondary antagonist of Disney's Stitch: Experiment 626 prequel video game.
Cromwell is MacKenzie's butler in the Touch Detective series. He is a supernatural being of some sort.
Dr. Curt Connors is a scientist in the Marvel Universe who transforms into the vile Lizard, usually fighting Spider-Man.
A non-player character in Kingdoms of Amalur: Reckoning.
The protagonist for Frictional Games' "Amnesia: The Dark Descent". Waking up with no memory of anything except his name and home address, Daniel finds a letter which warns him that he had done something so terrible that the only way he could live with himself was to erase his memories.
Dee Dee is Dexter's troublesome sister. She will often intrude in his laboratory and play around destroying things in the process.
Dexter is a boy super genius who has built a secret laboratory in his room. This leads to him inventing some crazy things and is the focal point of his adventures. He also has a mysterious German/Russianaccent.
A doctor who accidentally created a new breed of fire ants that ends up killing almost everyone in grayditch.
An important side character in Dead Island. Dr. West is working on an antidote for the zombification.
A famous inventor working in Winters and the father of Jeff from EarthBound.
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