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Dana Scully is Fox Mulder's partner in the FBI and was assigned to him to bring a skeptical point of view to his investigation into the X-Files
The intellectual opposite of Beavis and Butt-Head and a straight A student at Highland High School.
Mr David Van Driessen is the new age and hippie teacher to Beavis and Butt-Head.
A soldier put under a super-soldier program now uses 9X the amount of brainpower than the average human.
Desmond Lockheart is a character that appears in the Fallout 3 expansion, Point Lookout. Desmond, a ghoul, is one of the main quest givers throughout the DLC.
Boy-genius, inventor of many supercomputers.
A very talented scientist and inventor, who after years of designing F-Zero machines decided to enter the GP itself.
Possibly the smartest character in the Marvel Universe, Victor has invented time machines, and is a sorcerer.
A doctor who accidentally created a new breed of fire ants that ends up killing almost everyone in grayditch.
Is the main villain in the crash bandicoot games. And a mad scientist who's plan is always thwarted by Crash, who he created. He is thought to be a bit crazy.
A German scientist working as an adviser for Maverick. He is the one responsible for supplying Raiden with many of the items he needs.
The tech-head and tinkerer of the Teenage Mutant Ninja Turtles.
A famous inventor working in Winters and the father of Jeff from EarthBound.
Bulma's father and founder and first president of the Capsule Corporation. He is also Trunks' grandfather.
This mad scientist gave himself a cockroach head in an experiment he performed on himself. Although brilliant, he likes to eat garbage.
The evil Dr. Doofenshmirtz is constantly trying to take over the Tri-State Area. His nemesis is Perry the Platypus.
Dr. Dorson is an archaeologist and professor who asks for the aid of Ethan Webar and the GUARDIANS to investigate a newly discovered RELICS site. He appears early in the game 'Phantasy Star Universe' and has a vague connection to Renvolt Magashi.
The mad scientist of Halloween Town.
The scientist who invented Kurt's iconic coil suit.
Springfield's local family doctor
Dr. Julius was the weird scientist of the USS Swinetrek, which was the ship of the Pigs in Space segment of The Muppet Show. His name is a parody of Dr. Strangelove.
Jumba Jookiba is the alien mad scientist/"evil genius" from the "Lilo & Stitch" franchise. The creator of Stitch and his experiment "cousins", he is actually not really as evil as he likes to claim. His best friend is Pleakley, who he was initially forced to work with. On Earth, he pretends to be Lilo and Nani Pelekai's "uncle".
Blake Stone's nemesis in both Blake Stone games. He plans to take over earth using mutants, monsters, and modified humans.
Dr. Robotnik, also known as Dr. Eggman, is the antagonist in nearly every Sonic the Hedgehog title.
The polygonal floating doctor head from Brain Age. Rumour has it that he has a certain dislike for cilantro.
Dr. Wily is the insidious inventor of the various Robot Masters that plague the year 20XX. His jealousy and hatred for both Mega Man and Dr. Light has compelled him to mastermind various plots to do away with them throughout several games.
Edward is the resident computer genius on-board the Bebop. She is pretty wacky, and often seems to pursue her own agenda, but is an asset to the Bebop crew nonetheless.
Elexis Sinclaire is the sexy villain from SiN and SiN Episodes who became an avid cover girl for games magazines worldwide around the release of SiN.
Elrond Half-elven is a character in J. R. R. Tolkien's Middle-earth legendarium. He appears in many different Lord of the Rings games.
Emma Emmerich is Otacon's younger sister. The two were seperated in their youth, but were reunited for a short period of time in Metal Gear Solid 2.
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