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Abyss is the final boss in Marvel vs Capcom 2. He has three forms including a giant black statue man, a green ghost-like man, and a giant lava monster.
Apocalypse is a mutant who is over 5000 years old. He believes strongly in "the survival of the fittest." He was portrayed by Oscar Issac in the 2016 film X-Men: Apocalypse.
Arcade is a supervillain/hitman in the Marvel Universe. He assassinates his victims by kidnapping them and setting them loose in a maze of deathtraps disguised as an amusement park called Murderworld.
X-Men villain often associated with the Brotherhood of Mutants.
The Blob is a near invulnerable mutant from the Marvel Universe.
Count Luchino Nefaria is an "ionic vampire" super-villain.
A version of Hank McCoy from the Age of Apocalypse universe who harbors no morals and thus is a flat-out evil mad scientist. He's spent a lot of time on the mainstream Earth-616 universe, making trouble for the heroes there.
Deathbird is a supervillainess appearing in the Marvel Comics universe. She is part of the Shi'ar race.
Doctor Doom is a supervillain from the Marvel Universe who is bent on world domination. He is the ruler of Latveria and the primary antagonist of the Fantastic Four.
Donald Pierce is a member of the Hellfire Club, and a cybernetic villain. He also serves as the secondary antagonist of the 2017 film Logan.
An Inhuman with fire powers.
Infestation is a member of the Hellfire Academy, who is capable of controlling arthropods and storing them inside her body.
The Juggernaut is the stepbrother of Professor X. He gains his powers from a gem that allows him to become unstoppable.
God of the Klyntar symbiotes.
Krakoa is a living, mutant island and an enemy of the X-Men.
The leader of the Brotherhood of Mutants, Magneto has the power to control metal with his personal magnetic field. This generally has disastrous consequences as he believes that Mutants are superior to normal Humans and therefore, the Human race is expendable if it helps the Mutant cause.
Marrow is a mutant with accelerated bone growth which provides her both with armor and spiked bones to use as weapons.
The master Sentinel of the Marvel Universe, commonly associated with the X-Men.
Mastermind was one of the members of the original Brotherhood of Evil Mutants.
Mutant geneticist "Mr. Sinister" is a Marvel super-villain character that first appeared in Uncanny X-Men #221(1987).
Mystique is a shape-shifter that is known for her cunning, blue skin and athletic abilities. She is a villain in the X-Men franchise and a member of the Brotherhood of Mutants.
Obnoxio was the mascot for Marvel's humor magazine, Crazy. He once was hired for Kitty Pryde's birthday party, but the X-Men assumed he was a villain.
Omega Red (Arkady Rossovich) is a fictional character that appears in comic books published by Marvel Comics. The character first appeared in X-Men #4 (vol. 2, January 1992), and was created by Jim Lee and John Byrne.
Onslaught is a villain in the Marvel Universe, created when Professor Charles Xavier erased the mind of Magneto, and his psychic essence combined with the evil in Xavier's mind... or something.
Raze is the son of Mystique and Wolverine.
Sabretooth is the primary enemy of Wolverine. He has adamantium laced claws, a healing factor, and enhanced strength.Sabretooth was created by Chris Claremont and he first appeared in Iron Fist #14.Sabretooth's real name is Victor Creed.
Pterodactyl-like X-Men villain native to the Savage Land. Forced to drain the life force of others to sustain himself, Karl Lykos lives a miserable existence. If his victim happens to be a mutant, the drained force sets off a terrifying transformation.
Sebastian Shaw is a member of the Hellfire Club and a prominent X-Men villain
The COTA-94 model of Sentinel has been hunting down mutants and other characters in Capcom fighting games since X-Men: Children of the Atom. It is a distinct model, different from other Sentinels in the Marvel Universe.
A dragon who bestows great power upon anyone that can kill him. Resurrects after death, giving him the title "The Undying".
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