There are oblique worldbuilding/character spoilers from 15:00 to 19:30, one gameplay spoiler from 21:15 to 22:15, then intermittent very mild character spoilers up until 28:30 when thematic and story spoilers start. From 35:15 there's a spoiler-free conclusion.
Overall, they never talk about or show the major developments of the plot; rather they talk freely about the themes and inspirations behind the game.
Savage's comments