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Adam Jensen is a former Special Operative and director of security at Sarif Industries, a bio-tech firm specializing in human augmentation. After an attack leaves him gravely wounded, his entire body is "upgraded" with cybernetic augmentations to save his life. He is the main character of Deus Ex: Human Revolution.
Agent 47 is the main protagonist of the Hitman franchise; including games, films and novels. His name is derived from the last two digits off the barcode tattooed on the back of his head (640509-040147) as well as the fact he has 47 chromosomes.
The protagonist of Prototype, Alex Mercer has been transformed by a virus into a shapeshifting weapon. He seeks to uncover the mysterious source of his abilities as well as fight the same virus as it consumes Manhattan.
A highly skilled assassin during the Third Crusade, Altaïr is the unruly protagonist in Assassin's Creed.
Protagonist of Assassin's Creed III: Liberation. She is the first female lead in the series, and is being painted as a murderous villain by the Abstergo corporation, who seek to suppress the truth of her heroic nature.
In the Clay Fighter series Bad Mr. Frosty is a snowman with a bad attitude.
After witnessing the cold-blooded murder of his parents, young Bruce Wayne swore to combat the evil that took their lives. Using his family's fortune, he travelled the world, training to physical and mental perfection. Once his training was complete, he returned to Gotham City as the Dark Knight, Batman.
Cole is the protagonist of inFamous. He gains electricity-based superpowers in the explosion that cripples his hometown, and must choose whether to use them to defend or destroy Empire City. He has a tendency to slowly think out his choices and their possible consequences.
Commander Shepard is the main protagonist of the Mass Effect trilogy. Throughout the game, the player's decisions can affect Shepard's personality, consequently changing how both individuals and entire races view him/her and the human race. Key choices can even affect the outcomes of situations throughout the story.
Ratonhnhaké:ton (pronounced Ra-don-ha-gay-don), also known as Connor is a Native American Assassin in colonial America during the latter half of the 18th century. He, like Altaïr and Ezio, is an ancestor of Desmond Miles.
Dante is the star of Capcom's Devil May Cry series and the son of the Legendary Dark Knight Sparda. He is also the owner of his own business as a demon hunter, stationed at his Devil May Cry shop along with Trish.
An Italian poet in real life, and a scythe-wielding hero in the game Dante's Inferno.
Desmond Miles is, arguably, the main character of the Assassin's Creed franchise. He is a descendant of Altair, Ezio, and Connor, three of history's greatest assassins.
Nobleman of Florence, and the main protagonist of the Assassin's Creed II "trilogy". In Assassin's Creed II, Ezio is on a journey of vengeance. In Assassin's Creed: Brotherhood, he unites Rome against the Templars. In Assassin's Creed: Revelations, he seeks to find out how it will all end.
The main character of the Castlevania: Lords of Shadow saga. He was a knight of the Brotherhood of Light during the 11th century, but fell to darkness in order to save the world, and is now feared by all mankind as Dracula, lord of the vampires.
The protagonist of Dragon Age II. Hawke is a refugee from Lothering, who barely escaped the Blight's invasion and over a decade, became the Champion of Kirkwall.
The father and arch-enemy of Connor Kenway, protagonist of Assassin's Creed III, Haytham is a dedicated and skilled member of the Templar Order, believing that only through control can mankind reach its true potential. He is also the son of Edward Kenway, the protagonist of the subsequent title Assassin's Creed IV: Black Flag.
Heihachi Mishima is a character in the Tekken series. He has appeared in every Tekken game thus far and plays an important role in the central storyline that focuses on a deep-seated blood rivalry in the Mishima family.
The main character in Dead Space, Clarke is a Systems Engineer for the Concordance Extraction Corporation, sent to the USG Ishimura on a routine maintenance mission, where he discovers the nightmarish truth behind the downfall of the ship and its crew.
Jak is an orphan who battles to save the world along with his furry friend Daxter.
Son of Kazuya Mishima and Jun Kazama. Jin is a master of traditional Karate, having abandoned the Mishima style following the events of Tekken 3. Jin is now one of the main characters of the series. He has inherited the Devil Gene from his father.
Kazuya is a character in the popular 3D fighting game series Tekken. He is one of the central characters and a villain protagonist in the series, and was the victor of the first King of Iron Fist Tournament. He uses the Mishima based karate.
Marcus Fenix is the lead protagonist of the Gears of War series. A war hero who turned into a prison inmate for a rash decision, he is now humanity's last hope against the Locust Horde and the leader of Delta Squad.
Max Payne is the protagonist of the Max Payne series of games. After being unable to prevent the brutal murders of his wife and child, Max loses his grip on reality and dives right into the belly of the criminal underworld to serve up some vigilante justice.
Nathan "Rad" Spencer is the lead character in the Bionic Commando series. His original name remains unclear with indications towards both Radd and Ladd Spencer.
Jake "Nomad" Dunn is the main character in Crysis. He wears a prototype military suit with body-enhancing nanotechnology that can grant him superhuman strength, incredible speed, and the ability to turn invisible.
Everyone's favorite ghost-chasing, power-pellet-eating, dot-hunting yellow circle.
Saren Arterius is the main antagonist in first Mass Effect. He is also the longest serving Turian agent in the elite SPECTRES.
The protagonist of the franchise which bears his name, Sly Cooper is a gentleman thief and anthropomorphic raccoon, the latest inheritor of the Cooper legacy of master thieves. He is the last serviving member of his clan.
Solid Snake is the main protagonist in a number of the Metal Gear games. An expert in infiltration and espionage, Snake has completed countless missions and is repeatedly tasked with disarming the latest incarnation of Metal Gear. He is voiced by David Hayter in the English versions, Akio Ohtsuka in Japanese.
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