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The High Elf leader of the Mythic Dawn, Mankar Camoran made his appearance late in the main campaign of Elder Scrolls IV. A difficult enemy to defeat thanks to his magic, he has puzzled many, due to the fact that he was able to wear the Amulet of Kings.
Medusa is often portrayed in games as a creature that is a cross between a woman and a snake. The lower body is often a snake tail, and the hair is usually a mass of snakes. Other than this, the head and torso are that of a woman.
Mehrunes Dagon first appeared in The Elder Scrolls: Arena and is the Daedric Prince of Destruction, Change, Revolution, Energy, and Ambition.
Mephiles the Dark is one of the main villains of Sonic the Hedgehog (360 & PS3) he has a striking resemblance to Shadow the Hedgehog.
A twisted creature created by Shang Tsung, Mileena possesses a fragile mind and a ferocious bite. When not devouring the flesh of her enemies, she dreams of murdering her twin "sister" Kitana so that she may usurp her as Princess of Edenia.
Female Cyborg of the Winds of Destruction in Metal Gear Rising: Revengence.
The last boss of Serious Sam: Second Encounter.
The first major boss to be encountered in Painkiller, the Necrogiant is one of Lucifer's top generals.
The Necromancer is the second to last boss in the game Castle Crashers. He can raise undead foes to fight the knights.
A giant wearing a tribal mask, wielding a giant sword. He also holds a shield to, you know, protect himself against attacks.
Onslaught is a villain in the Marvel Universe, created when Professor Charles Xavier erased the mind of Magneto, and his psychic essence combined with the evil in Xavier's mind... or something.
"My art will be your demise"
Originally Mickey Mouse's arch-enemy, Pete has served as an antagonist in numerous Disney cartoons. In the realm of video games he is most commonly known as the henchman of Maleficent in the Kingdom Hearts series.
One of the many evil-doers in Bikini Bottom, Planktons life goal is to get a Krabby Patty and use its secret formula to make his restaurant (Chum Bucket) a success.
A robot master from Mega Man 6. His weapon is the Plant Barrier.
Prince Chan is the ruler of planet Chi-Fang. He loves to sing, eating lollipops and eating birthday attendees. Sam ruined his party by inviting himself over.
Jimmy's main enemy.
A sentient tentacle created by Dr. Fred with eventual evil aspirations of world domination.
Male Khajiit. He's in league with Kurdan gro-Dragol and works for him as a sharpshooter.
An evil entity who consumes people's memories. It was created from the cataclysmic event that brought Miasma to the world.
Rajan is an enemy of Sly Cooper and a member of the Klaww Gang. He used the black market to illegally sell spices to make money for the gang.
One of the Five Grand Cardinals. Rodyle was a shrewd and ambitious Desian who secretly plotted to overthrow their leader, Pronyma, and become the new leader of the Cardinals.
U.S. Senator representing Colorado running for president in 2020 in Metal Gear Rising: Revengeance.
A robot master from Mega Man 3. His weapon is the Shadow Blade.
Who's the evil resurrector and right-hand man of the Prince of Darkness himself? I'm talking 'bout Shaft. He is one bad motherf-shut your mouth!
One of the main badguys of "The World Ends With You", and a total math freak.
Sigma is the main antagonist in the Mega Man X series. He is almost always found to be the final boss in the games.
A demon from the Gothic franchise. The Sect Camp members worshipped it, believing it would deliver them from the Valley of Mines.
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