The key to most difficult fights in this game (including this one) is freeze which causes them to lose several turns.
I always used the gas bombs with a freeze mod on it. Even though it doesnt really do damage it debuffs everything with freeze (and sometimes gross out- in this fight the gross out does work). The gross out will cause damage constantly ( a pretty decent amount) and the freeze will let you attack more often. The gas bombs specifically because you can throw them 6 times so you have more odds of hitting everybody.
I also recommend using a very high damage weapon (I used the lords of the underworld axe with a fire mod once I got it all the way to the end of the game because it heals on perfect hit and does a substantial amount of damage). This has the effect of also adding a substantial fire hit every round on top of the gross out damage. If you have the perks which raise gross and fire damages then every time they take the DoT they'll be hit for a couple thousand (usually after their attack).
After that it's just a matter of doing a lot of damage and minimizing your own debuffs and HP loss. Kyle is good because he removes certain debuffs when you use his buff (which you can do every turn) and he does a ton of damage with summon elemental. Interestingly this attack doesn't cost a lot of PP so you can do it more often than you'd think. It's the most OP attack in the game honestly. It's kind of weird they didn't balance it but just take advantage of that.
Stan is also good because he can lower defense every turn and does decent AoE damage.
I didn't find this fight that hard, but I fought him at like lvl 12 or something. Mainly it's just key to keep them frozen, grossed out, and burning and do a lot of damage when you attack. It can be a cake walk.
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