So I have finally gotten to the U.S.S. Reagen and after failing for the last hour to even make a dent in his health bar, I have decided to take a break for awhile. My question is that if I turn off my PS3 at this stage of the game, where will I be able to continue from? Will I be able to start from the aircraft carrier, or will I have to go all the way back to where you are chasing him down in the tank?

I'm pretty sure that the save file would load you back up at the beginning of the boss fight, but I'm not 100% sure. Also, I find that grabbing the numerous missiles laying about and throwing them at the boss works rather well. I managed to beat him on my first try by doing that and then grabbing a couple dudes to replenish my health...just rinse and repeat.

thats exactly how I beat him aswell

I also think it'll let you start at the beginning of the fight

Thanks for the info. I ended up kicking his ass pretty easilly by just spamming the triangle whip attack over and over. Then once he started doing his devastator attack i'd move way off and consume people if i needed it. Once I hit the 30% marker and the timer started I just blew all my critical mass on the critical pain devestator and he died pretty easilly. Just had to jump out of the way every now and then. Really was kind of a push over using this strategy.